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Postdoctoral Research Associate - Cell Biology - Biomedical & Nutritional Sciences

Apply now Job no: 514638
Position type: Staff Full Time
Benefit Status: Benefited-Union
Campus: UMass Lowell
Department: Biomed & Nutritional Sciences
Salary: Salary commensurate with experience and grant
Applications Open:
Applications Close:

General Summary of Position:

The interactions between immune cells, epithelium and stressors determine the inflammation status of a host. It is widely accepted that the chronic inflammation is linked to several metabolic diseases including inflammatory bowel disease, atherosclerosis, obesity, and cancers. In the current project, we will use the normal and tumor enteroid model where enteroids mimicking the in vivo epithelial cells will be isolated from human intestine after surgical resection or from the biopsies. Several microbial products will be used as a stressor to test their effect in the integrity of the gut barrier and micronutrients will be used to determine their preventive effect. If the gut barriers are disrupted, then the harmful components can cross the epithelial layer and can interact with phagocytes including macrophages. The role of macrophages will be assessed in different disease stages. Primarily the transcriptomic and proteomic datasets will be used, and the predicted candidates will be validated in the patient-derived blood monocytes and tissue specific macrophages. This study will advance our understanding of the role of epithelial-immune cell crosstalk in chronic diseases including cancers and enhance our ability to design new targeted therapy.

Minimum Qualifications (Required):

Education:

  • PhD in cell biology, biochemistry, and related fields AND track record of publications on cancer and immunology (must have Ph.D. by the time of appointment)

Experience:

  • A strong background and research experiences in biochemistry, immunology, and cell biology
  • A research background in the application and/or knowledge in primary cells, isolation of monocytes from blood and stem cell biology would be useful

Skills:

  • Ability to work as a team player
  • Strong technical report writing and communication skills
  • Quantitative research methods and statistics

Special Instructions to Applicants:

Only current UML Employees within the Grants & Contracts (MTA/GRACE) bargaining unit will be considered during the first 10 business days of the posting. All other candidates will be considered after that period.

Initial review of applications will begin immediately and continue until the position is filled. However, the position may close when an adequate number of qualified applications is received.   

This position is contingent upon funding.  The initial appointment will be for one year with a possibility of renewal based on productivity, successful performance and the availability of funding.

Please include a resume and cover letter with your application. Names and contact information of three references will be required during the application process.  

 

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The University of Massachusetts Lowell is committed to increasing diversity in its faculty, staff, and student populations, as well as curriculum and support programs, while promoting an inclusive environment. We seek candidates who can contribute to that goal and encourage you to apply and to identify your strengths in this area.

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Please read this "EEO is the Law" poster (pdf), which provides an overview of many relevant equal opportunity laws.